Table 2.
Fasted and mean postraprandial mesenteric arterial blood flow, ghrelin, peptide YY3-36 (PYY), adrenaline and noradrenaline and subjective composite satiety score (CSS) evaluation before (PRE) and after (POST) the 10-day NORMOXIA and HYPOXIA confinements.
| Fasted state | Postprandial state | |||||
|---|---|---|---|---|---|---|
| Confinement | Time (min) | |||||
| 0 | 30 | 60 | 90 | 120 | ||
| MESENTERIC ARTERIAL BLOOD FLOW (ml·min−1) | ||||||
| NORMOXIA | Pre | 149.7 ± 6.7 | 530.6 ± 26.1 | 400.6 ± 20.7 | 279.0 ± 13.9 | 263.6 ± 14.7 |
| Post | 131.8 ± 8.5 | 593.1 ± 20.8 | 409.5 ± 14.7 | 316.5 ± 13.7 | 251.7 ± 10.3 | |
| HYPOXIA | Pre | 146.0 ± 8.0 | 627.1 ± 29.4 | 455.9 ± 22.8 | 287.0 ± 13.8 | 233.6 ± 10.5 |
| Post | 142.8 ± 5.4 | 646.0 ± 19.1 | 420.5 ± 9.6 | 332.4 ± 13.2 | 316.2 ± 12.2 | |
| GHRELIN (pg·ml−1) | ||||||
| NORMOXIA | Pre | 1190.4 ± 34.2 | 1057.4 ± 22.2 | 959.9 ± 22.8 | 971.5 ± 22.8 | 962.1 ± 24.3 |
| Post | 1163.3 ± 35.2 | 1010.7 ± 26.8 | 950.2 ± 23.4 | 842.9 ± 25.7 | 835.6 ± 24.6 | |
| HYPOXIA | Pre | 1030.4 ± 32.4 | 921.2 ± 19.2 | 864.6 ± 19.6 | 830.1 ± 23.5 | 830.2 ± 19.4 |
| Post | 1176.8 ± 32.4 | 1015.0 ± 24.0 | 935.6 ± 23.1 | 911.4 ± 21.9 | 919.6 ± 31.1 | |
| LEPTIN (ng·ml−1) | ||||||
| NORMOXIA | Pre | 3.02 ± 0.19 | ||||
| Post | 3.56 ± 0.22 | |||||
| HYPOXIA | Pre | 2.60 ± 0.21 | ||||
| Post | 3.63 ± 0.26 | |||||
| PYY (pg·ml−1) | ||||||
| NORMOXIA | Pre | 100.0 ± 37.5 | 128.6 ± 31.1 | 118.1 ± 23.2 | 111.5 ± 21.0 | 131.9 ± 22.7 |
| Post | 114.9 ± 28.8 | 144.6 ± 28.7 | 126.1 ± 24.6 | 129.5 ± 21.6 | 128.2 ± 24.3 | |
| HYPOXIA | Pre | 97.7 ± 27.2 | 128.8 ± 41.5 | 118.0 ± 35.6 | 125.8 ± 33.7 | 122.1 ± 33.7 |
| Post | 107.2 ± 19.4 | 142.8 ± 30.1 | 133.9 ± 31.4 | 137.1 ± 30.9 | 139.9 ± 31.1 | |
| ADRENALINE (nmol·l−1) | ||||||
| NORMOXIA | Pre | 0.31 ± 0.01 | 0.19 ± 0.01 | 0.21 ± 0.01 | 0.22 ± 0.01 | 0.26 ± 0.01 |
| Post | 0.27 ± 0.01 | 0.15 ± 0.01 | 0.21 ± 0.01 | 0.21 ± 0.01 | 0.22 ± 0.01 | |
| HYPOXIA | Pre | 0.30 ± 0.02 | 0.20 ± 0.02 | 0.18 ± 0.00 | 0.16 ± 0.01 | 0.24 ± 0.01 |
| Post | 0.26 ± 0.01 | 0.16 ± 0.01 | 0.18 ± 0.00 | 0.17 ± 0.01 | 0.22 ± 0.01 | |
| NORADRENALINE (nmol·l−1) | ||||||
| NORMOXIA | Pre | 0.89 ± 0.02 | 1.02 ± 0.03 | 0.99 ± 0.03 | 0.98 ± 0.02 | 0.94 ± 0.03 |
| Post | 0.77 ± 0.02 | 0.91 ± 0.02 | 0.81 ± 0.02 | 0.84 ± 0.03 | 0.86 ± 0.03 | |
| HYPOXIA | Pre | 1.01 ± 0.03 | 1.19 ± 0.04 | 1.01 ± 0.03 | 0.99 ± 0.02 | 1.03 ± 0.03 |
| Post | 1.30 ± 0.04* | 1.52 ± 0.07 | 1.49 ± 0.05 | 1.52 ± 0.06 | 1.47 ± 0.05 | |
| CSS EVALUATION (mm) | ||||||
| NORMOXIA | Pre | 31.8 ± 2.0 | 53.1 ± 2.9 | 53.8 ± 3.4 | 41.8 ± 2.8 | 34.9 ± 2.8 |
| Post | 31.1 ± 2.1 | 47.2 ± 2.7 | 44.4 ± 2.7 | 40.8 ± 2.5 | 38.0 ± 2.6 | |
| HYPOXIA | Pre | 38.3 ± 2.2 | 55.9 ± 2.9 | 53.9 ± 2.8 | 48.0 ± 2.4 | 46.0 ± 2.6 |
| Post | 37.3 ± 2.0 | 55.2 ± 2.9 | 55.3 ± 2.9 | 45.9 ± 2.8 | 44.6 ± 2.8 | |
Values are mean ± SEM, n = 11.
CSS, composite satiety score;
*,
significant differences between pre and post confinement; p < 0.05.