Table 1.

Association of 5-hmC levels with clinicopathological factors of LSCC patients (75th interquartile as a cutoff point)

Variables	Cases (n = 114)	Low 5-hmC	High 5-hmC	P
Age, years				0.997
≤ 60	59	44	15
> 60	55	41	14
Gender				0.144
Male	108	79	29
Female	6	6	0
Smoking				0.039
No	23	21	2
Yes	91	64	27
TNM stage				0.602
I/II	44	34	10
III/IV	70	51	19
Tumor invasion				0.004
T1/T2	65	55	10
T3/T4	49	30	19
LNM				0.388
N	75	54	21
Y	39	31	8
Tumor grade				0.718
1	18	15	3
2	82	57	25
3	14	13	1
Survival status				0.452
Alive	38	30	8
Dead	76	55	21