Table 3.
Prognostic value of clinicopathological factors and 5-hmC content in univariate and multivariate Cox regression analysis (n = 114)
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
|
|
|
|||
| Hazard Ratio (95% CI) | P | Hazard Ratio (95% CI) | P | |
| Age, years | ||||
| ≤ 60 | 1.00 (reference) | 1.00 (reference) | ||
| > 60 | 1.309 (0.825-2.076) | 0.253 | 1.133 (0.682-1.884) | 0.630 |
| TNM stage | ||||
| I/II | 1.00 (reference) | 1.00 (reference) | ||
| III/IV | 1.593 (0.946-2.682) | 0.080 | 1.437 (0.802-2.575) | 0.223 |
| LNM | ||||
| No | 1.00 (reference) | 1.00 (reference) | ||
| Yes | 1.349 (0.836-2.177) | 0.219 | 1.259 (0.775-2.046) | 0.352 |
| 5-hmC | ||||
| High | 1.00 (reference) | 1.00 (reference) | ||
| Low | 0.936 (0.563-1.555) | 0.798 | 0.953 (0.574-1.582) | 0.853 |