Table 1.
Epidemiological and sampling characteristics as well as the qPCR and MLVA results of the 104 mRDT-positive samples collected from four sites in Mali
| Study sites | Djoliba | Kolle (K) Samako (S) | Bamako | Bougoula | Total |
|---|---|---|---|---|---|
| Sampling period | October 2013 to January 2014 | November 2014 (K) | December 2014 | January 2015 | |
| December 2014 (K) | January 2015 | ||||
| January 2015 (K) (S) | |||||
| Endemicity*† | Hyperendemic | Hyperendemic | Hypoendemic | Hyperendemic | |
| Patients sampled, no. | 34 | 27 | 28 | 15 | 104 |
| Positive PCR for Plasmodium falciparum, n (%) | 29 (85.3) | 24 (88.9) | 20 (71.4) | 10 (66.7) | 83 (79.8) |
| Complete genotype (N = 8 loci), n (%) | 28 (96.5) | 21 (87.5) | 18 (90.0) | 8 (80.0) | 75 (90.4) |
| Genetic diversity (mean ± SD) | 0.76 ± 0.18 | 0.75 ± 0.16 | 0.78 ± 0.17 | 0.69 ± 0.36 | 0.75 ± 0.22 |
MLVA = multiple loci variable number of tandem repeats analysis; mRDTs = malaria Rapid Diagnostic Tests; qPCR = quantitative polymerase chain reaction; SD = standard deviation.
Data from various Malian official reports and studies reviewed in a published thesis in French. (Doumbo O, 1992. Epidémiologie du paludisme au Mali, étude de la chloroquinorésistance, essai de stratégie de contrôle basée sur l'utilisation de rideaux imprégnés de permethrine associée au traitement systématique des accès fébriles. Thèse de Doctorat. Sciences Biologiques, Montpellier II, France.)
Malaria endemicity levels based on P. falciparum prevalence among children aged 2–10 years (PfPR2–10), according to the World Health Organization classification: hypoendemic, 0–10%; hyperendemic, 50–75%.