Figure 4.

Abscisic acid (ABA) supplementation of mice decreased parasite transmission to Anopheles stephensi. (A). Daily percent parasitemia of control and ABA-supplemented mice infected with Plasmodium yoelii. Three mice were used per group. (B) Gametocytemia on day 5 postinfection, measured as the proportion of gametocytes in infected red blood cells. (C) Mean proportions of mosquitoes that became infected after feeding on control or ABA-supplemented mice. Bars represent three to four combined cohorts per treatment. Each cohort consisted of 30–40 mosquitoes fed on a single mouse. Data were analyzed by Fisher's exact test. (D) Oocysts per midgut of infected mosquitoes that fed on control or ABA-supplemented mice. Medians are shown. Data were analyzed by the Mann–Whitney test. * P ≤ 0.05, ** P ≤ 0.001