Fig 1.

Increased expression of NFATc1 in atopic children with asthma. A,NFATc1 gene transcript isoforms or variants. B, Schematic representation of the PreDicta analysis. C,NFATc1 mRNA expression was analyzed by using quantitative real-time PCR in PBMCs (n = 12-17 children per group). D, Children shown in Fig 1, C, were further subdivided into healthy children with negative skin test results (n = 5) and asthmatic children with positive skin test results (n = 13). E,IFNG mRNA expression analyzed by using quantitative real-time PCR in RNA isolated from whole blood (n = 6 and 15 children per group). F, Schema of the subjects and their obtained gene expression profiles from Asthma BRIDGE Cohort. Statistical significance in this figure was evaluated with the Student t test. *P ≤ .05 and **P ≤ .01. Data are presented as means ± SEMs.