Table III.

Comparison between different groups of children and adults with or without asthma and atopy (Asthma BRIDGE)

Group comparisons	Asthma +, skin test + (n = 251)
Asthma −, skin test + (n = 44)	P = .1
Asthma +, skin test − (n = 47)	P = .006 (NFATc1 isoform A)
Asthma −, skin test − (n = 75)	P = .002 (NFATc1 isoform A); P = .05 (NFATc1 isoform D)

For analysis using a microarray, there were 47,009 tag probes to target individual exons, including 4 exon sequences linked to specific NFATc1 isoforms. The particular isoforms of NFATc1 mRNA were as follows: NFATc1 isoform A = variant 1; NM 172390.2; NP 765978.1; NFATc1 isoform D = variant 4; NM 172388.2; NP 765976.1; Gene ID: 4772. P values for association of probes with phenotypes were adjusted by using the Benjamini-Hochberg method for multiple comparisons between groups.