Table 1.
Quantitative analysis data of acetone as its 2,4-dinitrophenylhydrazone derivative in human blood by HPLC.
Sample | Subject | Sex | Age | Blood glucose | Urine ketone | Acetone levels by HPLC (mean value ± sd.)∗ |
---|---|---|---|---|---|---|
Blood (mmol L−1)∗∗ | ||||||
Group 1 | ||||||
1 | Type 1 diabetes mellitus, Hashimoto disease, systemic lupus erythematosus | F | 21 | 197 | ++ | 15.00 ± 1.00 |
2 | Diabetes mellitus (DM), pneumonia | M | 68 | 320 | + | 2.40 ± 0.20 |
3 | DM, obesity, depression | F | 33 | 196 | + | 3.86 ± 0.10 |
4 | Acute pancreatitis | M | 60 | 134 | + | 0.013 ± 0.001 |
5 | Acute pancreatitis, obesity, hyperlipidemia | F | 33 | 117 | + | 0.22 ± 0.01 |
6 | DM | F | 37 | 175 | + | 0.24 ± 0.01 |
7 | Gestational DM | F | 37 | 74 | +++ | 17.27 ± 1.00 |
| ||||||
Group 2 | ||||||
8 | DM, hypothyroidemia | M | 80 | 340 | − | 0.42 ± 0.01 |
9 | DM, hypertension | F | 82 | 248 | − | 3.20 ± 0.10 |
10 | DM, hypertension, cerebrovascular disease, acute kidney failure | F | 77 | 202 | − | 3.10 ± 0.10 |
11 | Anemia, hypothyroidemia, hyperlipidemia | M | 52 | 110 | − | 0.033 ± 0.01 |
12 | DM, hypertension, hyperlipidemia | F | 55 | 137 | − | 1.53 ± 0.01 |
13 | Hypertension, congestive heart disease, chronic obstructive pulmonary disease, cerebrovascular disease | M | 83 | 182 | − | 1.51 ± 0.01 |
14 | DM, larynx carcinoma, hypothyroidemia | M | 59 | 177 | − | 1.54 ± 0.01 |
15 | Hepatic failure, hypertension, chronic kidney failure | M | 87 | 111 | − | 2.13 ± 0.10 |
∗Number of repeated experiments, n = 4, and ∗∗reference value: 0.034–0.120 mmol L−1 with a mean value in plasma: 0.075 mmol L−1 (n = 20) [2].