Skip to main content
. 2016 Jan 28;44(10):4595–4609. doi: 10.1093/nar/gkw042

Figure 1.

Figure 1.

High reproducibility of ChIP-Seq peaks in pairs of co-expressed genes. Jaccard coefficients show reproducibility for the following sets of gene pairs: cRPGs (n = 4851 pairs); mRPGs (n = 3486); HE_NRGs (high-expression NRGs, n = 14 196, see Materials and Methods); NRG_A's (diverse gene pairs co-expressed with R ≥ 0.9, n = 17 846); NRG_B's (diverse gene pairs co-expressed with 0.9 > R ≥ 0.8, n = 759 316); and NRG_C's (a sample of independently expressed, diverse gene pairs, abs(R) < 0.1, n = 100 000). TR binding in NRG_C's is about 50% less reproducible than in co-expressed gene sets, indicating that a large portion of the binding events in gene regions is functional.