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. 2016 Jun 2;6:27067. doi: 10.1038/srep27067

Figure 3. Reassortants (Gt7, 12, 13 and 17) of EA/FJ04 and pdm/BJ09 viruses exhibited a spectrum of lung histopathology at 4 days post infection.

Figure 3

(A) Gt7 and (B) Gt13 viruses caused severe bronchopneumonia and interstitial pneumonia with erosion of epithelial lining (open arrow), widespread infiltrate of monocytic cells (triangle) and interstitial edema around blood vessels (solid arrow). (C) Parental pdm/BJ09 and (D) Gt17 virus infection resulted in less severe bronchopneumonia with edema, erosion of epithelial lining (open arrow) and some infiltration of monocytic cells (triangle) around blood vessels (solid arrow). (E) Parental EA/FJ04 and (F) Gt12 viral infections were least severe with reduced erosion of epithelial cells (open arrow) and few monocytic inflammatory cells (triangle) around blood vessels (solid arrow). Lung sections were stained with hematoxylin and eosin. Scale bar = 100 μm.