Table 1. Characteristics of the study population.
| LOAD (N = 254) | VaD (N = 115 ) | Control (N = 435) | ||
|---|---|---|---|---|
| mean ± SD | ||||
| Age | 79.8 ± 6.3 | 79.8 ± 6.1 | 73.2 ± 5.8 | |
| MMSE score | 18.7 ± 5.1 | 15.2 ± 6.3 | NA | |
| SPMSQ (number of errors) | NA | NA | 0.1 ± 0.4 | |
| N (%) | ||||
| Female | 162 (64) | 66 (57) | 232 (53) | |
| Education | ≦6 years | 128 (51) | 69 (60) | 50 (12) |
| 6–12 years | 86 (34) | 34 (30) | 171 (39) | |
| >12 years | 37 (15) | 12 (10) | 212 (49) | |
| Ever smoking | 60 (24) | 32 (28) | 75 (17) | |
| Alcohol consumption | 28 (11) | 19 (17) | 48 (11) | |
| Hypertension | 96 (38) | 75 (65) | 232 (53) | |
| Diabetes mellitus | 48 (19) | 40 (35) | 62 (14) | |
| Hypercholesterolemia | 46 (18) | 25 (22) | 133 (31) | |
| APOE ε4 status | 99 (39) | 26 (23) | 65 (15) | |
Cases (LOAD or VaD) were compared to controls. Numbers in bold indicate significant findings (P < 0.05). Abbreviations: LOAD, late-onset Alzheimer’s disease; VaD, vascular dementia; SD, standard deviation; MMSE, Mini-Mental State Exmination; SPMSQ, Short Portable Mental Status Questionnaire; NA, not applicable; APOE, apolipoprotein E.