Figure 3.

Morphology of cigarette smoke induced changes in the testicular tissues of rats. H&E stain for pathological assessment. (A) Testis from sham-exposed rat. (B)–(D) Section of testis from rat exposed to 10, 20, and 30 nonfilter cigarettes/day for 2 weeks. (E)–(G) Section of testis from rat exposed to 10, 20, and 30 nonfilter cigarettes/day for 4 weeks showing the disturbance in the various stages of spermatogenesis. (H)–(J) Section of testis from rat exposed to 10, 20, and 30 nonfilter cigarettes/day for 6 weeks and the arrow indicating the atrophic tubules. (K)–(M) Section of testis from rat exposed to 10, 20, and 30 nonfilter cigarettes/day for 8 weeks showing the wider spacing of intercellular. (N)–(P) Section of testis from rat exposed to 10, 20, and 30 nonfilter cigarettes/day for 12 weeks and the arrow indicating the vacuolization and cell debris of Sertoli cells. The decrease in the total count of spermatogonia, spermatocytes, spermatids, Leydig cells, and Sertoli cells was also noticed.