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. 2016 Jun 2;7:204. doi: 10.3389/fimmu.2016.00204

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Copyright © 2016 Ley, Pramod, Croft, Ravichandran and Ting.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression in resident tissue-specific macrophages (microglia, lung, liver, spleen, intestinal, adipose) and bone marrow-derived macrophages (BMDM) for comparison. Heat maps based on hierarchical clustering results from microarray and RNA-Seq data for (A) apoptosis receptors, (B) complement receptors, (C) toll-like receptors, (D) NOD-like receptors, (E) RNA and DNA sensors, (F) C-type lectins, (G) scavenger receptors, (H) integrins, (I) tumor necrosis factor receptor superfamily, (J) Fc receptors, (K) G-protein-coupled receptors, and (L) cytokine receptors. Gene expression levels are expressed in log₂ values, differences shown in color scale after Z-score transformation. Colors scale bar ranges from red (+3) to green (−3). Light gray indicates undetectable.

Gene expression in resident tissue-specific macrophages (microglia, lung, liver, spleen, intestinal, adipose) and bone marrow-derived macrophages (BMDM) for comparison. Heat maps based on hierarchical clustering results from microarray and RNA-Seq data for (A) apoptosis receptors, (B) complement receptors, (C) toll-like receptors, (D) NOD-like receptors, (E) RNA and DNA sensors, (F) C-type lectins, (G) scavenger receptors, (H) integrins, (I) tumor necrosis factor receptor superfamily, (J) Fc receptors, (K) G-protein-coupled receptors, and (L) cytokine receptors. Gene expression levels are expressed in log₂ values, differences shown in color scale after Z-score transformation. Colors scale bar ranges from red (+3) to green (−3). Light gray indicates undetectable.