Table 4.
Effect of host and HIV-1 viral factors on day 7 and 28 changes in HIV-1 plasma viral load
| Variables | Categories | HIV-1 VL0–7 (N = 30) | HIV-1 VL0–28 (N = 22) | ||||
|---|---|---|---|---|---|---|---|
| Mean rank | U/χ2 (df) | p value | Mean rank | U/χ2 (df) | p value | ||
| HBV status | HIV alone | 10.00 (n = 11) | 44.0 | 0.300 | 12.20 (n = 10) | 33.0 | 0.218 |
| Co-infection | 13.00 (n = 11) | 8.80 (n = 10) | |||||
| Sex | Male | 12.86 (n = 7) | 43.0 | 0.503 | 15.35 (n = 9) | 19.0 | 0.020 |
| Female | 10.87 (n = 15) | 8.29 (n = 11) | |||||
| WHO clinical stage | Stage 1 | 4.25 (n = 2) | 2.794 (2) | 0.247 | 9.00 (n = 1) | 0.068 (2) | 0.966 |
| Stage 2 | 12.09 (n = 17) | 10.56 (n = 16) | |||||
| Stage 3 | 13.00 (n = 3) | 10.67 (n = 3) | |||||
| Antiretroviral drugs | d4T + 3TC + EFV | 11.00 (n = 2) | 0.737 (3) | 0.864 | 10.50 (n = 2) | 3.182 (3) | 0.364 |
| d4T + 3TC + NVP | 12.83 (n = 6) | 9.75 (n = 4) | |||||
| CBV + EFV | 12.25 (n = 8) | 13.13 (n = 8) | |||||
| CBV + NVP | 10.06 (n = 8) | 7.50 (n = 6) | |||||
| Mutations | Present | 5.75 (n = 2) | 8.5 | 0.292 | 9.5 (n = 4) | 26.0 | 0.878 |
| Absent | 10.75 (n = 17) | 10.75 (n = 16) | |||||
| HIV-1 subtype | 02AG | 10.41 (n = 17) | 24 | 0.410 | 9.5 (n = 4) | 37 | 0.898 |
| Non 02AG | 13.50 (n = 4) | 10.75 (n = 16) | |||||
Significant p values are in italics
U, Mann–Whitney U test; χ2 (df), Kruskal–Wallis H test; Co-infection, HIV and HBV co-infection; VL 0–7 HIV-1 plasma viral load changes after 7 days of therapy; VL 0–28 HIV-1 plasma viral load changes after 28 days of therapy