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. Author manuscript; available in PMC: 2016 Jun 2.
Published in final edited form as: Chem Res Toxicol. 2014 Feb 13;27(4):674–682. doi: 10.1021/tx500011m

Table 1.

Parameters of DMPO-adducts formed from nucleosides following treatment with hydralazine (125 μM) and Cu2+(25 μM) at room temperature.

Substrate Hyperfine Coupling Constants, G Assignment
aN aH aN
2′-deoxyadenosine 15.42 19.95 2.58 N-centered, exocyclic NH2

2′-deoxycytidine 15.38 18.95 2.02 N-centered

Thymidine 15.88 19.5 2.71 N-centered

2′-deoxyguanosine 15.6 20.27 2.56 N-centered, N3 position

ESR-Spin trapping studies were carried out as described in the Methods Section.