Table 4.
Weighted logistic regression to analyse the relationship between microglial protein load (%) and dementia status in participants with and without Alzheimer’s dementia
| Microglia (load (%)) | OR | 95 % CI (OR) | P |
|---|---|---|---|
| Iba1 | 0.86 | (0.82; 0.89) | <0.001 |
| CD68 | 3.55 | (1.93; 6.51) | <0.001 |
| HLA-DR | 1.06 | (0.96; 1.18) | 0.250 |
| MSR-A | 1.56 | (1.11; 2.19) | 0.010 |
| CD64 | 1.21 | (1.05; 1.39) | 0.007 |
These analyses only included participants without dementia or with dementia with Alzheimer’s pathology. Significant positive association (bold); significant negative association (italic)