Table 7.
Linear regression analyses investigating the relationship between Alzheimer’s pathology and the MMSE score in participants with and without dementia
| Alzheimer’s pathology | No dementia | Dementia with Alzheimer’s pathology | ||||
|---|---|---|---|---|---|---|
| β | 95 % CI (β) | P | β | 95 % CI (β) | P | |
| Meningeal CAA | 0.48 | (−2.87; 3.82) | 0.779 | 0.49 | (−3.25; 4.24) | 0.794 |
| Parenchymal CAA | −3.63 | (−9.33; 2.07) | 0.210 | 1.67 | (−3.04; 6.39) | 0.482 |
| Diffuse plaques | 0.74 | (−0.67; 2.15) | 0.299 | 0.50 | (−3.45; 4.45) | 0.800 |
| Neuritic plaques | 0.24 | (−1.61; 2.09) | 0.797 | −2.43 | (−5.84; 0.99) | 0.161 |
| Tangles | 1.83 | (−3.90; 7.56) | 0.528 | −4.12 | (−7.60; −0.65) | 0.021 |
These analyses only included participants without dementia or with dementia with Alzheimer’s pathology. Significant negative association (italic)