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. 2016 Jun 2;13:135. doi: 10.1186/s12974-016-0601-z

Table 7.

Linear regression analyses investigating the relationship between Alzheimer’s pathology and the MMSE score in participants with and without dementia

Alzheimer’s pathology No dementia Dementia with Alzheimer’s pathology
β 95 % CI (β) P β 95 % CI (β) P
Meningeal CAA 0.48 (−2.87; 3.82) 0.779 0.49 (−3.25; 4.24) 0.794
Parenchymal CAA −3.63 (−9.33; 2.07) 0.210 1.67 (−3.04; 6.39) 0.482
Diffuse plaques 0.74 (−0.67; 2.15) 0.299 0.50 (−3.45; 4.45) 0.800
Neuritic plaques 0.24 (−1.61; 2.09) 0.797 −2.43 (−5.84; 0.99) 0.161
Tangles 1.83 (−3.90; 7.56) 0.528 4.12 (−7.60; −0.65) 0.021

These analyses only included participants without dementia or with dementia with Alzheimer’s pathology. Significant negative association (italic)