Table 3.
Prevalence of prescriptions of potentially inappropriate medications for specific diagnoses or conditions for elderly patients (N = 523,811)a
| Disease or syndrome | Male (n = 212,082) No (%b) | Female (n = 311,729) No (%b) | Total (n = 523,811)No (%b) | |||
|---|---|---|---|---|---|---|
| Cardiovascular | ||||||
| Heart failure (n = 66,119) | 11,624 | (17.58) | 25,003 | (37.82) | 36,627 | (55.40) |
| Syncope (n = 4,871) | 573 | (11.76) | 509 | (10.45) | 1,082 | (22.21) |
| Central nervous system | ||||||
| Chronic seizures or epilepsy (n = 16,940) | 2,357 | (13.91) | 3,502 | (20.67) | 5,859 | (34.59) |
| Delirium (n = 3,906) | 1,410 | (36.10) | 1,801 | (46.11) | 3,211 | (82.21) |
| Dementia and cognitive impairment (n = 53,992) | 13,557 | (25.11) | 29,767 | (55.13) | 43,324 | (80.24) |
| History of falls or fractures (n = 76,721) | 10,844 | (14.13) | 34,504 | (44.97) | 45,348 | (59.11) |
| Insomnia (n = 68,919) | 7,668 | (11.13) | 13,876 | (20.13) | 21,544 | (31.26) |
| Parkinson's disease (n = 13,662) | 557 | (4.08) | 1,277 | (9.35) | 1,834 | (13.42) |
| Gastrointestinal | ||||||
| Chronic constipation (n = 112,212) | 26,920 | (23.99) | 44,320 | (39.50) | 71,240 | (63.49) |
| History of gastric or duodenal ulcers (n = 173,326) | 30,178 | (17.41) | 58,069 | (33.50) | 88,247 | (50.91) |
| Kidney and urinary tract | ||||||
| Chronic kidney disease Stages IV and V (n = 12,511) | 4,153 | (33.19) | 3,650 | (29.17) | 7,803 | (62.37) |
| LUTS/BPHc in men (n = 68,096) | 37,826 | (55.55) | - | 37,826 | (55.55) | |
| Urinary incontinence (all types) in women (n = 28,368) | - | 118 | (0.42) | 118 | (0.42) | |
| Stress or mixed urinary incontinence (n = 6,759) | - | 369 | (5.46) | 369 | (5.46) |
aThe prevalences were significantly different between male and female for each diagnosis or condition (P<0.0001); bPercentages (%) with respect to male, female, and total populations for each diagnosis or condition, respectively; cLUTS/BPH, lower urinary tract symptoms/benign prostatic hyperplasia