Table 2. Identification of picked proteins differentially expressed between KO villus and KO crypt.

Spot No.a	Accession No.b	Genec	Protein Name	Protein MW (kDa)	Protein PI	Average fold changed	Overall trend
1118	P50544	Acadvl	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	70.8	8.75	2.61	Down
1266	P68373	Tuba1c	Tubulin alpha-1C chain	49.9	5.10	−2.15	Up
1320	Q3TEN9	Gyk	Glycerol kinase	57.4	5.76	−2.64	Up
1496	Q8VH52	Eif4a1	Eukaryotic translation initiation factor 4A1	16.1	5.15	2.78	Down
1732	Q9D154	Serpinb1a	Leukocyte elastase inhibitor A	42.5	6.21	−3.20	Up
1794	Q3TJ66	Aldob	Fructose-bisphosphate aldolase	39.5	8.27	−2.06	Up
1800	B2CY77	Rpsa	Laminin receptor	32.8	4.87	4.23	Down
1952	P14869	Rplp0	60S acidic ribosomal protein P0	34.2	6.25	−3.78	Up
2346	Q9Z1R9	Prss1	protease, serine 1 (trypsin 1)	26.1	4.94	4.23	Down
2529	Q3U0B3	Dhrs11	Dehydrogenase	28.3	6.34	−3.33	Up
3254	E9Q223	Hbb-bs	Protein Hbb-bs	11.1	6.37	18.87	Down
3261	P51162	Fabp6	Gastrotropin	14.5	6.15	−6.16	Up

^aSpot No. generated by DeCyder image analysis software (v 7.0, GE Healthcare), referencing the spots shown on the representative image in Supplementary Fig. 5.

^bAccession number from NCBI database.

^cGene symbol from NCBI database. All genes are Mus musculus.

^dAverage ratio of protein expression.