Table 1.

Participant Characteristics

Participant	Age (years)	Gender	Sterol Ratio†	U-MVA‡	24S+	Severity Score*
1	14.33	Male	0.039	0.863	47.6	11.0
2	10.33	Male	0.39	4.928	41.13	35.0
3	5.83	Male	0.34	0.763	51.7	38.0
4	8.25	Female	0.47	0.850	47.2	25.0
5	5.17	Female	0.08	1.503	78.4	–
6	17.33	Female	0.09	1.573	43.3	10.0
7	16.50	Female	0.09	1.530	32.5	10.0
8	1.00	Female	0.65	0.385	–	–
9	5.58	Male	0.19	1.420	64.1	20.0
10	10.00	Male	0.10	1.286	65.6	30.0
11	4.92	Male	0.37	0.628	46.88	–
12	5.93	Female	0.09	0.444	–	5.0
13	3.92	Male	0.14	0.308	–	5.0
14	6.58	Male	0.00	0.594	109	20.0
15	3.08	Female	0.04	–	–	–
16	18.17	Female	0.70	1.201	24.6	33.0
17	15.42	Female	0.23	–	–	10.0
18	5.92	Male	0.06	0.610	132	6.0
19	1.08	Female	0.75	0.300	40.0	40.0
20	11.92	Female	0.042	0.184	–	17.0

Note.

^†= (7-DHC+8-DCH)/Cholesterol;

^‡= Mevalonic Acid via Urine (μmol/day);

⁺24(S)-hydroxycholesterol;

^*= SLOS Clinical Severity Score (21, 22).