Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 14;5(4):418–423. doi: 10.1242/bio.016279

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 5. — Administration of AT132 can effectively suppress the development of arthritis in TgTC mice. Sections of the knee joint at 8 weeks of age: wild-type mice (A), TgTC mice treated by saline weekly (B) and TgTC mice treated by AT132 at 1.25 mg/kg weekly (C) are shown. Thickening of the synovial layer (arrow) is completely suppressed in the antibody-treated transgenic mice. Treatment by AT132 at 1.25 mg/kg weekly can inhibit hTNFα production in synovial tissue of TgTC mice (D) (TgTC, 5635±585.7 pg/g; TgTC+AT132 1.25 mg/kg, 151.6±14.92 pg/g). Data presented as mean±s.e.m. Asterisk indicates a significant difference between saline- and AT132-treated samples. ***P<0.001 (t-test), Scale bars=200 μm.