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. 2016 Jun 2;11(6):e0156774. doi: 10.1371/journal.pone.0156774

Table 2. HULC expression cut-off based on predictive probability of clinical outcome among the OS patients.

Gene Cut-off* Sensitivity % Specificity % PPV % NPV % Accuracy % AUC
(CI) (CI) (CI) (CI) (CI) (CI)
HULC 0.000048 50.0 73.7 58.3 66.7 64.6 0.48
(23.0–76.9) (48.8–90.8) (27.7–84.8) (43.0–85.4) (50.4–76.5) (0.25–0.70)

*The optimal cutoff was determined as the point at which it simultaneously maximized sensitivity and specificity

PPV: positive predictive value; NPV: negative predictive value. CI: 95% confidence interval.