Table 2. HULC expression cut-off based on predictive probability of clinical outcome among the OS patients.
Gene | Cut-off* | Sensitivity % | Specificity % | PPV % | NPV % | Accuracy % | AUC |
---|---|---|---|---|---|---|---|
(CI) | (CI) | (CI) | (CI) | (CI) | (CI) | ||
HULC | 0.000048 | 50.0 | 73.7 | 58.3 | 66.7 | 64.6 | 0.48 |
(23.0–76.9) | (48.8–90.8) | (27.7–84.8) | (43.0–85.4) | (50.4–76.5) | (0.25–0.70) |
*The optimal cutoff was determined as the point at which it simultaneously maximized sensitivity and specificity
PPV: positive predictive value; NPV: negative predictive value. CI: 95% confidence interval.