Table 1. Association of personal characteristics at enrollment with mean Physical Component Summary (PCS) and Mental Component Summary (MCS) scores from the VR-12, for survivors at 5 year follow-up in the Seattle Colorectal Cancer Family Registry.
| N (%) | PCS | MCS | |||||
|---|---|---|---|---|---|---|---|
| Difference in Mean PCS | (95%CI) | P | Difference in Mean MCS | (95%CI) | P | ||
| Age (y)a | |||||||
| <50 | 228 (22) | ref. | <0.001 | ref | <0.001 | ||
| 50–59 | 272 (27) | -1.5 | (-3.4, 0.3) | 2.6 | (1.1, 4.1) | ||
| 60–69 | 337 (33) | -3.1 | (-5.0, -1.2) | 4.5 | (3.0, 6.0) | ||
| ≥70 | 184 (18) | -5.9 | (-8.0, -3.7) | 3.7 | (1.9,5.4) | ||
| Sex | 0.001 | 0.001 | |||||
| Male | 530 (52) | ref | ref | ||||
| Female | 491 (48) | -2.3 | (-3.6, -0.9) | -1.7 | (-2.8, -0.7) | ||
| BMI (kg/m2)b | <0.001 | 0.70 | |||||
| <25 | 335 (33) | ref | ref | ||||
| 25–29.9 | 408 (40) | -0.9 | (-2.4, 0.6) | -0.3 | (-1.5, 0.9) | ||
| ≥30 | 278 (27) | -3.7 | (-5.6, -1.9) | 0.2 | (-1.2, 1.6) | ||
| Marital Statusa | 0.49 | 0.66 | |||||
| Not married | 259 (25) | -0.5 | (-2.1, 1.0) | -0.3 | (-1.5, 1.0) | ||
| Married or living as married | 762 (75) | ref | ref | ||||
| Race | 0.22 | 0.73 | |||||
| White | 933 (91) | ref | -0.3 | (-2.2, 1.6) | |||
| Other | 88 (9) | 1.3 | (-0.8, 3.4) | ref | |||
| Educationa | <0.001 | 0.19 | |||||
| High school or less | 318 (31) | -1.5 | (-3.2, 0.3) | -0.6 | (-1.9, 0.8) | ||
| Some college or technical education | 335 (33) | ref | ref | ||||
| College graduate | 368 (36) | 2.4 | (0.8, 4.0) | 0.6 | (-0.6, 1.7) | ||
| Cigarette Smokinga | <0.001 | 0.11 | |||||
| Never | 414 (41) | ref | ref | ||||
| Former | 502 (49) | -1.5 | (-2.9, -0.1) | -0.3 | (-1.4, 0.8) | ||
| Current | 105 (10) | -5.5 | (-8.1, -2.9) | -2.3 | (-4.5, 0.2) | ||
| Colorectal Co-morbiditiesa,c | 0.049 | 0.16 | |||||
| None | 837 (82) | ref | ref | ||||
| One or more | 184 (18) | -1.8 | (-3.5, 0.0) | -1.0 | (-2.4, 0.4) | ||
| Diabetesa,d | <0.001 | 0.18 | |||||
| No | 899 (88) | ref | ref | ||||
| Yes | 122 (12) | -5.0 | (-7.4, -2.6) | -1.2 | (-2.9, 0.6) | ||
| Stage at Diagnosis | 0.12 | 0.57 | |||||
| Local | 517 (51) | ref | ref | ||||
| Regional | 454 (44) | -0.5 | (-1.9, 0.9) | -0.8 | (-1.9, 0.2) | ||
| Distant | 30 (3) | -1.1 | (-5.7, 3.6) | 1.9 | (-0.2, 4.1) | ||
| Unstaged or unknown | 20 (2) | -6.3 | (-11.6, -1.1) | -0.8 | (-4.7, 3.1) | ||
| Site of Tumor | 0.59 | 0.74 | |||||
| Colon | 619 (61) | ref | ref | ||||
| Rectum | 349 (34) | -0.7 | (-2.1, 0.7) | 0.2 | (-0.9, 1.3) | ||
| Unknown | 53 (5) | -0.8 | (-3.9, 2.3) | -0.7 | (-2.9, 1.6) | ||
| Intercept e | 52.5 | (50.4, 54.8) | 53.2 | (51.4, 55.1) | |||
a At Colon Cancer Family Registry enrollment.
b Two years prior to baseline interview.
c Self-report of physician diagnosis of colitis, Crohns disease, diverticulitis, or irritable bowel syndrome.
d Self-report of physician diagnosis of diabetes.
e The intercept from the linear regression model is the mean PCS and MCS among (hypothetical) individuals in the referent category for all variables.