Table 2.
Predictive value of K-RAS mutations on overall survival in patients treated with chemotherapy.
| Author | Setting | Total number of patients | K-RAS mutations (%) | Survival (HR/P value) |
|---|---|---|---|---|
| Tsao et al. [24] | Adjuvant | 450 | 26.0 | 0.95/0.87 |
| Tsao et al. [37] | Adjuvant | 1751 | 19.7 | 1.18/0.09 |
| Camps et al. [38] | Advanced | 308 | 8.8 | NR/0.51 |
| Kalikaki et al. [39] | Advanced | 162 | 22.6 | NR/0.52 |
HR: hazard ratio; NR: not reported.