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. 2014 May 14;2014:190976. doi: 10.1155/2014/190976

Table 1.

In vitro Huntington's disease models.

Cell line Number of glutamines in the polyQ tract Full- length/truncated mutant protein Reporter Reference
HEK-293 82 N-Terminal part of Htt protein with 171 amino acids None [14]

HeLa
A 459
Sh-SY5Y
128 N-Terminal part of Htt protein with 171 amino acids Enhanced green fluorescent protein [15]

Cos-7
SH-SY5Y
neuro-2A
49, 72, 151 Full length of exon-1 Enhanced green fluorescent protein [4]

HEK 293 60, 150 N-Terminal part of exon-1 Enhanced green fluorescent protein [16]

PC-12 103 N-Terminal part of exon-1 Ecdysone inducible system [17]

HEK 293
PC-12
150 N-Terminal part of exon-1 None [7]