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. 2016 Feb 14;7(8):8556–8579. doi: 10.18632/oncotarget.7388

Figure 4. a. The GEN of old women and b. the associated functional network.

Figure 4

a. The upper left circle represents the TFs (119), the lower left circle represents the miRNAs (94), and the big right circle represents the proteins (1388) for the GEN of old women. Links within the “proteins” circle represent PPIs, links between the “TFs” circle and the “proteins” circle represent regulation of TFs on target genes, and links between the “miRNAs” circle and the “proteins” circle represent regulation of miRNAs on target genes in the GEN of old women. b. In the functional network of the GEN of old women, the first six enriched GO terms (biological processes) are regulation of transcription, regulation of RNA metabolic process, regulation of apoptosis, intracellular signaling cascade, RNA processing, and regulation of cell proliferation. The number in parentheses represents the number of proteins involved in each function.