Table 1. Pathway analysis of proteins in the GEN of elderly individuals.
Pathway analysis | ||
---|---|---|
KEGG pathway | Numbers | p-value |
Pathways in cancer | 42 | 1.7E-4 |
Neurotrophin signaling pathway | 19 | 2.4E-3 |
MAPK signaling pathway | 32 | 3.5E-3 |
NOD-like receptor signaling pathway | 12 | 3.5E-3 |
Cytosolic DNA-sensing pathway | 10 | 1.4E-2 |
B cell receptor signaling pathway | 12 | 1.5E-2 |
ErbB signaling pathway | 13 | 1.8E-2 |
Toll-like receptor signaling pathway | 14 | 2.4E-2 |
In the GEN of elderly individuals, the first eight enriched KEGG pathways are pathways in cancer, the Neurotrophin signaling pathway, MAPK signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, B cell receptor signaling pathway, ErbB signaling pathway, and Toll-like receptor signaling pathway.