Table 2. Pathway analysis of core proteins in the specific core GEN of elderly individuals during the aging process.

Pathway analysis
KEGG pathways	Numbers	p-value
Toll-like receptor signaling pathway	5	9.1E-2
T cell receptor signaling pathway	5	1.1E-1
Fc epsilon RI signaling pathway	3	2.0E-1
Neurotrophin signaling pathway	4	3.8E-1
Wnt signaling pathway	4	4.8E-1
MAPK signaling pathway	5	5.5E-1

In the specific core GEN of elderly individuals, the first six enriched KEGG pathways are the Toll-like receptor signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, Wnt signaling pathway, and MAPK signaling pathway.