Table 1. The RA-related pathways based on SNP dataset (FDR<0.05).
| Pathway ID | Pathway name | P-value | FDR | Function class |
|---|---|---|---|---|
| hsa04145 | *Phagosome | 0 | 0 | Cellular Processes; Transport and catabolism |
| hsa04514 | *Cell adhesion molecules (CAMs) | 0 | 0 | Environmental Information Processing; Signaling molecules and interaction |
| hsa04612 | *Antigen processing and presentation | 0 | 0 | Organismal Systems; Immune system |
| hsa04672 | *Intestinal immune network for IgA production | 0 | 0 | Organismal Systems; Immune system |
| hsa04940 | *Type I diabetes mellitus | 0 | 0 | Human Diseases; Endocrine and metabolic diseases |
| hsa05140 | *Leishmaniasis | 0 | 0 | Human Diseases; Infectious diseases |
| hsa05145 | *Toxoplasmosis | 0 | 0 | Human Diseases; Infectious diseases |
| hsa05150 | *Staphylococcus aureus infection | 0 | 0 | Human Diseases; Infectious diseases |
| hsa05168 | *Herpes simplex infection | 0 | 0 | Human Diseases; Infectious diseases |
| hsa05310 | *Asthma | 0 | 0 | Human Diseases; Immune diseases |
| hsa05320 | *Autoimmune thyroid disease | 0 | 0 | Human Diseases; Immune diseases |
| hsa05330 | *Allograft rejection | 0 | 0 | Human Diseases; Immune diseases |
| hsa05332 | *Graft-versus-host disease | 0 | 0 | Human Diseases; Immune diseases |
| hsa05416 | *Viral myocarditis | 0 | 0 | Human Diseases; Cardiovascular diseases |
| hsa05164 | *Influenza A | 1.00E-05 | 0.00013 | Human Diseases; Infectious diseases |
| hsa05162 | *Measles | 0.00015 | 0.001831 | Human Diseases; Infectious diseases |
| hsa05323 | *Rheumatoid arthritis | 0.00038 | 0.004365 | Human Diseases; Immune diseases |
| hsa05152 | *Tuberculosis | 0.00102 | 0.011064 | Human Diseases; Infectious diseases |
| hsa05322 | *Systemic lupus erythematosus | 0.00468 | 0.048095 | Human Diseases; Immune diseases |
*
Pathways were reported as RA-related pathways in previous literatures.