Figure 3. Suppression of the down-stream target genes of NF-κB in non-polyp intestinal mucosa segments and/or polyp segments of Min mice with or without 5 ppm irsogladine maleate treatment.

Quantitative real-time PCR analyses were performed to determine the IL-1β A. IL-6 B. and IKBKB C. mRNA expression levels in the polyps or non-polyp intestinal mucosa of Min mice who received diets containing irsogladine maleate at doses of 5 ppm for 8 weeks. The data are normalized according to GAPDH and presented as the means ± SD. **p < 0.01, *p < 0.05 vs 0 ppm.