Table 1. Cytotoxic, antiviral activity and selectivity index of OM against EV71.
Compound | Cytotoxicity | Antiviral activitya | Selectivity Index |
---|---|---|---|
OM | CC50(μM) | IC50(μM) | SI (CC50/IC50) |
83.87±1.12b | 2.38±0.79b | 35.24 |
RD cells were infected with EV71 at a MOI of 0.01 after treatment with serial dilution of OM for 4 h.
Values obtained from nonlinear regression analysis using GraphPad Prism5.
Values represent the mean ± SD of three independent experiments.