Table 1. Correlation between the mRNA expressions of COL3A1 and clinicopathological variables in patients with colorectal cancer revealed by data-mining of Oncomine gene array datasets.

Dataseta	Clinicopathological parameters		Total cases	COL3A1b		χ2	p
				< M	≥ M
Bittner Colon (373)	T stage	Tis-T1	52	35	17	10.073	0.018
		T2	103	47	56
		T3	85	35	50
		T4	88	47	41
	Dukes stage	A	49	33	16	7.607	0.022
		B	101	49	52
		C-D	88	38	50
	Smoke	Never smoker	179	100	79	4.523	0.033
		Smoker	194	87	107
Smith Colorectal (177)	Stage	I	24	19	5	10.468	0.015
		II	57	27	30
		III	57	23	34
		IV	39	20	19
	Recurrence	No recurrence	109	62	47	7.502	0.006
		Recurrence	36	11	25
	Survival	Alive	104	64	40	12.78	0
		Dead	73	25	48
Jorissen Colorectal 3 (154)	Dukes stage	A	24	4	20	22.850	0.000
		B	54	24	30
		C	43	30	13
		D	33	19	14
	Recurrence	No recurrence	27	20	7	6.641	0.008
		Recurrence	92	40	52
	Age	20-49 years	16	12	4	9.491	0.050
		50 - 59 years	29	17	12
		60 - 69 years	43	20	23
		70 - 79 years	46	21	25
		80+ years	24	7	17
Lin Colon 2 (149)	Sex	Male	70	26	44	8.224	0.004
		Female	79	49	30
Vilar Colorectal 2 (104)	Age	40-59 years	22	16	6	10.650	0.014
		60 - 69 years	42	26	16
		70 - 79 years	73	29	44
		80+ years	39	17	22

^aThe analysis was performed using datasets from the Oncomine cancer gene expression microarray DB (https://www.oncomine.org/resource/login.html). The numbers in the blankets represent the total cases.

^bCOL3A1 mRNA expression was dichotomized into lower-than-median (< M) and higher-than-median (≥ M) groups.