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. 2016 Jan 22;7(8):8839–8849. doi: 10.18632/oncotarget.6983

Figure 5. Prostate oncosome levels distinguish localized PCa patients from metastatic PCa patients.

Figure 5

To enumerate prostate oncosomes, PSMA+ve MPs that were larger than 880nm silica beads were used to set the analysis gate (red gate, A.-D.. Cells are detected in the upper corner of E. and F.). Metastatic PCa patient cohorts exhibited significantly higher prostate oncosome levels compared to localized PCa patient cohorts G.. Furthermore, PSMA-high/LALS-high events were significantly higher in the CRPC cohort compared to all other paired comparisons. One-way ANOVA, * denotes p < 0.05. N > 20 for each group.