Figure 2. Clinical, pathological and molecular features of the patients investigated.

I: primary tumor; II: recurrent tumor (“site of recurrence” indicates the site from which sample II was taken), mut: mutation, the presence of somatic mutation is indicated by a black box, by an orange box when subclonal, and by a light blue box when present only in a few of the investigated specimens (indicated by numbers). Chromosomal anomalies are reported as follows: green, CN gain; red, CN loss; yellow, LOH; purple, allelic imbalance (AI), *anomalies < 1 Mb have not been reported. Δ, deletion of the only present allele. All data but those in the line with “FFPE” (formalin fixed paraffin embedded) tag refer to results obtained on frozen material. M, male; F, female; ^#local stage; B, blastemal component; E, epithelial component; S, stromal component; R, rhabdomyoblastic elements; D, diffuse anaplasia; NR, nephrogenic rests; PLNR, perilobar nephrogenic rests; RT, radiotherapy; OS, overall survival; DFS, disease-free survival; ^†dead of disease.