Table 2. Univariate analysis of factors associated with OS survival and recurrence.
| Variables | Overall survival | RFS | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | pvalue | Hazard ratio (95% CI) | pvalue | |
| Sex (Male vs. Female) | 1.660 (0.590-4.670) | 0.337 | 1.458(0.519-4.096) | 0.463 |
| Age (years) (<19 vs. ≥19) | 1.009 (0.983-1.037) | 0.506 | 1.012 (0.986-1.040) | 0.381 |
| Enneking stage (I/IIA vs. IIB/III) | 3.276 (1.157-9.219) | 0.017 | 3.225 (1.128-9.224) | 0.029 |
| Site of primary tumor (Femur vs. other) | 0.977(0.378-8.2022.524) | 0.962 | 1.077 (0.417-2.784) | 0.879 |
| Response to chemotherapy (good vs. poor/NA) | 3.029 (1.125-8.153) | 0.023 | 3.324(1.471-7.531) | 0.004 |
| Metastasis (negative vs. positive) | 11.062 (1.463-83.627) | 0.001 | 36.548 (4.632-288.356) | 0.001 |
| Cryablow vs.Cryabhigh | 2.772(1.085-7.083) | 0.033 | 3.719 (1.316-10.510) | 0.013 |
Abbreviations and Note: OS, Osteosarcoma; RFS, relapse-free survival; 95%CI, 95% confidence interval; HR, Hazard ratio; Cox proportional hazards regression model.