Table 2. Adverse event and survival ratios with MACH index for drug/comparator pairs.

Drug/Comparator	Adverse Events	Adverse Event ratio	Survival (mo)	Survival ratio	MACH Index
Bortezomib	0.75	1.25	29.8	1.26	0.99
Dexamethasone	0.60		23.7
Sunitinib	0.37	1.48	26.0	1.30	1.14
Interferon alpha	0.25		20.0
Regorafenib	0.54	3.86	6.40	1.28	3.02
Placebo	0.14		5.00
Sorafenib	0.11	2.06	10.7	1.28	1.62
Placebo	0.05		7.9
Erlotinib	0.65	1.12	12.3	1.11	1.01
Placebo	0.58		11.1