Table 1. Properties of the used OAd constructs.

Virus name	Abbreviation	Properties	Reference
Ad5/3	-	-	present work
Ad5/3-Luc	Luc	Luciferase gene fused via IRES to the fiber gene.	[23]
Ad5/3-Δ19K-.Luc	Luc/19K-	Luciferase gene fused via IRES to the fiber gene, deletion of E1B19K.	[23]
Ad5/3-TRAIL	TRAIL	Human TRAIL gene fused via IRES to the fiber gene.	[23]

All viruses have a 24 amino acid deletion in E1A for tumor-selectivity, an E3-deletion, an Ad5/3 chimeric fiber for enhanced cell entry and a GFP gene upstream of RITR, expressed from the major late promoter.