Figure 7. MiR-129 negative correlation with Notch-1 in glioma tissues and cell lines.
(A) Expression of miR-129 and Notch-1 mRNA in 16 malignant glioma and 8 normal brains tissues was analyzed by qPCR, indicating that miR-129 expression was significantly lower and (B) Notch-1 was significantly higher in malignant glioma than that of normal brain tissues (**P < 0.01, ***P < 0.001). (C) MiR-129 negative correlation with Notch-1 mRNA in glioma tissues (r = −0.673). (D) qPCR analysis of expression of miR-129 and Notch-1 mRNA in two glioma cell lines compared with normal brain tissues (**P < 0.01).
