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. 2016 Jan 25;7(8):9388–9403. doi: 10.18632/oncotarget.7011

Figure 2. The effects of PPD12 on ABCB1 mRNA and protein levels in MDR cells.

Figure 2

(A) mRNA expression of ABCB1 in KB, KB/VCR, MCF-7, MCF-7/ADM, HEK293, and HEK293-ABCB1 cells. (B) ABCB1 protein expression in KB, KB/VCR, MCF-7, MCF-7/ADM, HEK293, and HEK293-ABCB1 cells. (C) Neither varied concentrations of PPD12 after 48 h incubation nor 5 μM PPD12 for 72 h changed mRNA levels of ABCB1 in multi-drug resistant KB/VCR cells. (D) Neither varied concentrations of PPD12 afer 48 h incubation nor 5 μM PPD12 for 72 h changed ABCB1 protein levels in multi-drug resistant KB/VCR cells.