Table 3. Univariate analysis of risk factors for thrombosis in JAK2V617F-positive MPNs.
| Thrombotic group | Control group | P value* | |
|---|---|---|---|
| Number of patients (M:F) | 43 (26:17) | 138 (67:71) | 0.172 |
| Age (≥ 60 years) | 31/43 (72.1%) | 43/138 (31.16%) | < 0.001 |
| CV risk factors | 36/43 (83.72%) | 42/138 (30.43%) | < 0.001 |
| rs3733609 C/T genotype | 13/43 (30.2%) | 12/138 (8.7%) | < 0.001 |
| WBC (≥ 10 × 109/L) | 40/43 (93.02%) | 61/138 (44.2%) | < 0.001 |
| Hb (g/L) | |||
| < 160 | 24 | 67 | |
| 160–180 | 5 | 16 | |
| > 180 | 14 | 55 | 0.374 |
| Platelet (× 109/L) | |||
| < 300 | 5 | 22 | |
| 300–600 | 17 | 56 | |
| > 600 | 21 | 60 | 0.454 |
*
P based on chi-square test or the Mann-Whitney U-test. CV risk factor; cardiovascular risk factors including tobacco use, hypertension, or diabetes mellitus.