Figure 5. Antisecretive effects of Sirolimus and OSI-906, alone and in combination, after 3, 6 and 9 days of treatment in HepG2 and HuH-7 cell lines.

α-FP levels are expressed as percentage of control and represent the mean ± S.E.M. of three independent experiments for each cell line. Control is set as 100%. **P<0.01; ***P<0.001.