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. 2016 Jan 19;7(9):9732–9741. doi: 10.18632/oncotarget.6947

Figure 4. Stronger reduction in replication tract length in HR-deficient compared to HR-proficient HNSCCs after combined treatment.

Figure 4

(A) Examples of replication tracts after different treatments in HR-proficient and -deficient cells. (B and C) HR-proficient and HR-deficient HNSCCs were sequentially pulse-labeled with CldU followed by IdU and replication tract length (kb/min) was calculated. Replication tract length was plotted for single as well as combined treatment, relatively to untreated controls. (D) A stronger reduction in replication tract length was observed in the HR-deficient group (p = 0.04). Statistical analysis of at least three different experiments was performed using Student's t-test.