Figure 1. Specific cytotoxicity induced by Rh2E2 in cancer cell cultures.
A. Organic synthesis of Rh2E2. B. Cytotoxic effects of Rh2E2 on mouse lung cancer cells (LLC-1) and human normal lung fibroblasts (CCD19Lu). C. Cytotoxic effects of Rh2E2 toward a panel of cancer cells from different origins. D. Cytotoxic effects of 20(S)-Rh2 on LLC-1 and CCD19Lu cells. E. Cytotoxic effects of 20(R)-Rh2 on LLC-1 and CCD19Lu cells. Cell cytotoxicity was measured by MTT assay after 72 hr incubation. Representative results were shown as Means ± S.E.M. from 3 independent experiments.