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. 2016 Feb 2;7(9):9951–9963. doi: 10.18632/oncotarget.7127

Figure 1. High-resolution melting assays for the detection of SF3B1, SRSF2, and U2AF35 mutations.

Figure 1

Representative data for each of the hotspots are shown. (A) SF3B1 hotspot containing the N626D, R625G, and E622D detected in sample 10, 13, and 28, respectively. (B) SF3B1 hotspot containing the K666R, K666T, and H662Q mutations detected in sample 3, 8, and 9, respectively. (C) SF3B1 hotspot containing the K700E mutation detected in sample 31. (D) SRSF2 hotspot containing the P95L and P95H mutations detected in sample 25 and 27, respectively. (E) U2AF35 hotspot containing the Q157R mutation detected in sample 23. (F) U2AF35 hotspot containing the S34 mutations not detected in any of the samples.