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. 2016 Feb 2;7(9):9951–9963. doi: 10.18632/oncotarget.7127

Figure 4. Volcano plots of the P-values and fold changes in expression of the miRNAs.

Figure 4

Each miRNA is represented by a colored dot indicating its class. Blue represents canonical miRNA, red represents mirtron, and green represents SO miRNA. (A) Spliceosome mutated samples versus wild-type samples. It can be observed that all differentially expressed miRNAs were downregulated in the spliceosome mutated samples. (B) SF3B1 mutated samples versus wild-type samples. It can be observed that all differentially expressed miRNAs were downregulated in the samples containing an SF3B1 mutation. (C) SRSF2 mutated samples versus wild-type samples. It can be observed that all differentially expressed miRNAs were downregulated in the samples containing an SRSF2 mutation.