Table 1. Differentially expressed miRNAs between SF3B1 mutated patients and wild-type patients.
MiRNA | miRNA-class | Chr. | Host Gene | Transcribed direction | LFC | Tumor Suppressor | P-value |
---|---|---|---|---|---|---|---|
let-7c-5p | Canonical | 21 | MIR99AHG | Same | −2.13 | Yes | 0.001 |
let-7b-5p | Canonical | 22 | MIRLET7BHG | Same | −2.49 | Yes | 0.002 |
let-7f-5p let-7f-1 let-7f-2 |
−1.4 | Yes | 0.004 | ||||
Canonical | 9 | JB153432 | Same | ||||
Canonical | x | HUWE1 | Same | ||||
let-7a-5p let-7a-1 let-7a-2 let-7a-3 |
−1.67 | Yes | 0.005 | ||||
Canonical | 9 | JB153432 | Same | ||||
Canonical | 11 | MIRLET100 | Same | ||||
Canonical | 22 | MIRLET7BHG | Same | ||||
hsa-miR-423-5p | Canonical | 17 | NSRP1 | Same | −1.66 | Yes | 0.007 |
hsa-miR-103a-3p hsa-miR-103a-1 hsa-miR-103a-2 |
−0.87 | Yes | 0.009 | ||||
Canonical | 5 | PANK3 | Same | ||||
Canonical | 20 | PANK2 | Same | ||||
hsa-miR-26b-5p | Canonical | 2 | CTDSP1 | Same | −2.24 | Yes | 0.011 |
let-7i-5p | Canonical | 12 | No host gene | N/A | −1.09 | Yes | 0.011 |
hsa-miR-15a-5p | Canonical | 13 | DLEU2 | Same | −1.18 | Unknown | 0.011 |
hsa-miR-3605-5p | Mirtron | 1 | PHC2 | Same | −1.23 | Unknown | 0.030 |
hsa-miR-192-5p | Canonical | 11 | AB429224 | Same | −0.84 | Yes | 0.047 |
Abbreviations, Chr: Chromosome, LFC: log2 fold change.