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. 2016 Jan 28;7(9):10037–10050. doi: 10.18632/oncotarget.7048

Figure 1. Expression of CUL4A is upregulated in gastric cancer tissues and cell lines.

Figure 1

A. Western blotting results of CUL4A protein levels in different GC cell lines. CUL4A protein levels are higher in the six GC cell lines than in the human immortalized gastric epithelial cell line (GES-1). B. Western blotting results of CUL4A protein levels in GC tissues and adjacent noncancerous gastric tissues. CUL4A protein levels are higher in GC tissues (T) than in adjacent noncancerous gastric tissues (ANT) from the same patient (n=4). C. IHC staining of CUL4A protein in human GC (clinical stages I-IV) and normal gastric tissues. D. GC patient samples were stratified by CUL4A protein expression into low (45%) and high (55%) groups (n=124). E. Kaplan-Meier survival curves indicated that higher levels of CUL4A (n=68) are associated with lower patient survival rates than lower levels of CUL4A (n=56). Each bar represents the mean±SD of three independent experiments. *p-value <0.05.