Table 3. PFS and OS: stratification of 107 patients in two main groups with respect to hs-CRP changes after two months' therapy.

		PFS					OS
	No. patients	No. events	Median PFS (95% CI)	p	HR (95% CI)	p	No. events	Median OS (95% CI)	p	HR (95% CI)	p
Overall
Low – Low + High – Low	86	73	11.4(9.3–14.0)		1.00		57	25.2(22.3–29.2)		1.00
Low – High + High –High	21	21	8.6(6.1–10.3)	0.007	1.95(1.19–3.19)	0.008	17	15.3(11.5–28.6)	0.008	2.08(1.20–3.62)	0.009
CT arm
Low – Low + High – Low	40	35	11.3(9.0–15.0)		1.00		26	27.3(23.3–36.6)		1.00
Low – High + High – High	13	13	7.4(6.0–10.3)	0.017	2.19(1.13–4.24)	0.020	12	14.4(11.6–20.8)	0.0009	3.16(1.54–6.47)	0.002
CT + B arm
Low – Low + High – Low	46	38	11.9(9.1–14.9)		1.00		31	24.8(19.3–34.5)		1.00
Low – High + High – High	8	8	9.1(2.9–15.9)	0.204	1.64(0.76–3.54)	0.210	5	24.5(3.7-nr)	0.675	1.23(0.47–3.19)	0.675

nr:not reached.