Table 2. Number and costs of adverse drug reaction reports obtained with each intervention.

Approach	Intervention	Adverse drug reaction reports				Costs (€) per report
		Before		After
		2 years	1 year	1 year	2 years	Initial costs	Running costs (2 years)	Total
Protocols		0	0	204	117	0.47	1.49	1.96
Hyperlinks		153	120	277	132	15.59	0.00	15.59
Hyperlinks NPE*		68	47	146	110	15.03	0.00	15.03
Educational	1st workshop	36	24	257	68	0.78	19.53	20.31
	Pharmacies	2	8	110	25	1.60	40.00	41.60
	Health care centers	25	7	102	17	2.29	57.47	59.77
	Hospitals	9	9	45	26	3.77	94.34	98.11
Phone Interview		47	26	87	34	8.33	33.33	41.67
	Pharmacies	23	10	37	14	22.22	88.88	111.11
	Health care centers	3	1	8	2	66.67	266.67	333.33
	Hospitals	21	15	42	18	16.67	66.67	83.33
Educational	2nd workshop	54	40	106	30	4.76	119.05	123.81
	Pharmacies	39	25	69	18	8.70	217.39	226.09
	Health care centers	10	13	26	6	22.22	555.55	577.78
	Hospitals	5	2	11	6	20.00	500.00	520.00

* NPE: Not previously exposed. Considering only the institutions without any previous intervention.