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Local application of 4AP in the PC induces FR and SLE. The left panel illustrates the position of the recording electrodes and the site of the ejection pipettes filled with 2 mM 4AP. On the right, the effects of 100-msec local applications of 4AP (arrows) in the PC (upper panel) and in the l-EC (lower panel) are shown. FRs and SLEs are induced by local 4AP injection in PC. The arrowheads point to the negative deflection at the end of the SLE.
Epilepsia © ILAE
